</iframe</noscript> <!-- End Google Tag Manager (noscript) --> <a href="#main-content" class="visually-hidden focusable"> Skip to main content </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div class="body-page gva-body-page"> <div id="jpreContent"> <div id="jprecontent-inner"> <div class="preloader-wrapper hidden active"> <img src="https://scri.queensu.ca/themes/custom/gavias_financial/images/preloader/preloader-2.gif" alt="Preloader Image" /> </div> </div> </div> <header id="header" class="header-v1"> <div class="brand_header "> <div class="brand-header-inner"> <!--Queen's Utility Bar --> <div class="clearfix"> <div class="brand-header-content"> <div class="region region-brand-header"> <div id="block-emergencyalert" class="block block-emergency-alerts no-title"> <div class="content block-content"> <div id="quur-emergency-alerts"> </div> </div> </div> <div id="block-universalheader" class="block block-block-content block-block-contentbbaec8c8-893a-4c7b-9fd9-65aa7db31b19 no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qhs_utility_bar"> <section class="inner-wrapper container"> <a class="qu-logo" href="https://www.queensu.ca/" target="_blank" rel="noopener"> <img alt="Queen's Logo" src="/themes/custom/gavias_financial/overrides/img/Queens-logo-reversed.svg" /> </a> <section class="widget-wrapper"> <nav id="sign_in_widget"> <button> Sign In <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"> <path d="M233.4 406.6c12.5 12.5 32.8 12.5 45.3 0l192-192c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L256 338.7 86.6 169.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l192 192z" stroke-width="4"></path> </svg> </button> <div id="sign_in_menu"> <span>University Wide</span> <ul id="university_wide_links"></ul> <span>Faculty/School Portals</span> <ul id="portal_links"></ul> </div> </nav> <section id="search_widget"> <button id="search_button"> <svg class="glass-icon" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24"> <path d="M23,24c-.25,0-.51-.1-.7-.29l-7.66-7.55c-1.58,1.19-3.51,1.84-5.52,1.84C4.09,18,0,13.96,0,9S4.09,0,9.11,0s9.11,4.04,9.11,9c0,2.12-.77,4.18-2.13,5.79l7.61,7.5c.39,.39,.4,1.02,0,1.41-.2,.2-.45,.3-.71,.3ZM9.11,2c-3.92,0-7.11,3.14-7.11,7s3.19,7,7.11,7c1.83,0,3.57-.68,4.89-1.92,0,0,0,0,0,0,1.43-1.33,2.21-3.14,2.21-5.08,0-3.86-3.19-7-7.11-7Z"></path> </svg> <svg class="close-icon" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24"> <path d="M12 22C6.47715 22 2 17.5228 2 12C2 6.47715 6.47715 2 12 2C17.5228 2 22 6.47715 22 12C22 17.5228 17.5228 22 12 22ZM12 20C16.4183 20 20 16.4183 20 12C20 7.58172 16.4183 4 12 4C7.58172 4 4 7.58172 4 12C4 16.4183 7.58172 20 12 20ZM12 10.5858L14.8284 7.75736L16.2426 9.17157L13.4142 12L16.2426 14.8284L14.8284 16.2426L12 13.4142L9.17157 16.2426L7.75736 14.8284L10.5858 12L7.75736 9.17157L9.17157 7.75736L12 10.5858Z"></path> </svg> </button> <form id="search_form" role="search" action="//www.queensu.ca/qtbsearch/" method="get"> <div class="inner"> <label for="QUsearch"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24"> <path d="M23,24c-.25,0-.51-.1-.7-.29l-7.66-7.55c-1.58,1.19-3.51,1.84-5.52,1.84C4.09,18,0,13.96,0,9S4.09,0,9.11,0s9.11,4.04,9.11,9c0,2.12-.77,4.18-2.13,5.79l7.61,7.5c.39,.39,.4,1.02,0,1.41-.2,.2-.45,.3-.71,.3ZM9.11,2c-3.92,0-7.11,3.14-7.11,7s3.19,7,7.11,7c1.83,0,3.57-.68,4.89-1.92,0,0,0,0,0,0,1.43-1.33,2.21-3.14,2.21-5.08,0-3.86-3.19-7-7.11-7Z"></path> </svg> </label> <input class="" type="search" placeholder="Search pages or people" aria-label="Search pages or people" name="term" id="QUsearch" /> </div> </form> </section> </section> </section> </section></div> </div> </div> </div> </div> </div> <!--Site Title--> <div class="branding"> <div class="container"> <div class="region region-branding"> <div id="block-sitetitle" class="block block-block-content block-block-contentc3ecb934-0770-436d-ad29-6e876211d7a0 no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><a class="site-title" href="/">Sinclair Cancer Research Institute</a> </div> </div> </div> </div> <!--Mobile Menu Toggle Button --> <div id="menu-bar" class="menu-bar hidden-lg hidden-md"> <span class="one"></span> <span class="two"></span> <span class="three"></span> </div> </div> </div> <!--Main Menu--> <div class="area-main-menu"> <div class="area-inner container"> <div class="gva-offcanvas-mobile"> <div class="close-offcanvas hidden"> <i class="fa fa-times"></i> </div> <div class="region region-main-menu"> <nav role="navigation" aria-labelledby="block-gavias-financial-mainnavigation-menu" id="block-gavias-financial-mainnavigation" class="header-height block block-menu navigation menu--main"> <h2 class="visually-hidden block-title" id="block-gavias-financial-mainnavigation-menu"><span>Main navigation</span></h2> <div class="block-content"> <div class="gva-navigation"> <ul class="clearfix gva_menu gva_menu_main"> <li class="menu-item menu-item--expanded "> <a href="/about-us"> About Us <span class="icaret nav-plus fa fa-angle-down"></span> </a> <ul class="menu sub-menu"> <li class="menu-item"> <a href="/news"> News </a> </li> <li class="menu-item"> <a href="/about-us/members"> Members </a> </li> <li class="menu-item"> <a href="/about-us/newsletters"> Newsletters </a> </li> <li class="menu-item"> <a href="/about-us/seminar-series"> Seminar Series </a> </li> <li class="menu-item"> <a href="/about-us/affiliated-departments"> Affiliated Departments </a> </li> <li class="menu-item"> <a href="https://www.queensu.ca/cancergradprogram/"> Graduate Program </a> </li> </ul> </li> <li class="menu-item menu-item--expanded "> <a href="/cancer-research-divisions"> Cancer Research Divisions <span class="icaret nav-plus fa fa-angle-down"></span> </a> <ul class="menu sub-menu"> <li class="menu-item menu-item--collapsed"> <a href="/cancer-biology-genetics-cbg"> Cancer Biology & Genetics </a> </li> <li class="menu-item"> <a href="https://www.ctg.queensu.ca/"> Cancer Clinical Trials </a> </li> <li class="menu-item menu-item--collapsed"> <a href="/cancer-care-epidemiology"> Cancer Care & Epidemiology </a> </li> </ul> </li> <li class="menu-item menu-item--collapsed"> <a href="/patient-engagement-network"> Patient Engagement Network </a> </li> <li class="menu-item"> <a href="/contact-us"> Contact Us </a> </li> </ul> </div> </div> </nav> </div> </div> </div> </div> </div> </div> </header> <div class="breadcrumbs"> <div class="region region-breadcrumbs"> <div class="breadcrumb-content-inner"> <div class="gva-breadcrumb-content"> <div id="block-gavias-financial-breadcrumbs" class="text-dark block gva-block-breadcrumb hidden-xs block-system block-system-breadcrumb-block no-title"> <div class="container"> <div class="breadcrumb-content-main"> <h2 class="page-title hide">Blog </h2> <div class="hidden-breadcrumb-links"> <div class="content block-content"> <div class="breadcrumb-links"> <div class="content-inner"> <nav class="breadcrumb " role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> <span class=""> / </span> </li> <li> </li> <li> QCRI Zoom Seminar! Thurs. Feb. 8, 2024 at 4:00pm - Dr. Kathleen Watt </li> <li></li> </ol> </nav> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div role="main" class="main main-page"> <div class="clearfix"></div> <div class="clearfix"></div> <div class="clearfix"></div> <div id="content" class="content content-full"> <div class="container"> <div class="content-main-inner"> <div class="row"> <div id="page-main-content" class="main-content col-xs-12 col-md-8 sb-r "> <div class="main-content-inner"> <div class="content-main"> <div class="region region-content"> <div id="block-gavias-financial-content" class="block block-system block-system-main-block no-title"> <div class="content block-content"> <!-- Start Display article for teaser page --> <!-- Start Display article for detail page --> <article data-history-node-id="828" about="/news/research-news/qcri-zoom-seminar-thurs-feb-8-2024-400pm-dr-kathleen-watt" typeof="schema:Article" class="node node-detail node--type-article node--promoted node--view-mode-full clearfix"> <div class="post-block"> <div class="post-thumbnail post-standard"> <div class="field field--name-field-image field--type-image field--label-hidden field__item"> <div class="item"> <img property="schema:image" loading="lazy" src="/sites/scri/files/articles/KathleenWatt.jpg" alt="Kathleen Watt Seminar" typeof="foaf:Image" /> </div> </div> </div> <div class="post-content"> <h1 class="post-title"><span property="schema:name" class="field field--name-title field--type-string field--label-hidden">QCRI Zoom Seminar! Thurs. Feb. 8, 2024 at 4:00pm - Dr. Kathleen Watt</span> </h1> <span property="schema:name" content="QCRI Zoom Seminar! Thurs. Feb. 8, 2024 at 4:00pm - Dr. Kathleen Watt" class="rdf-meta hidden"></span> <span property="schema:interactionCount" content="UserComments:0" class="rdf-meta hidden"></span> <div class="post-meta"> <span class="post-categories"> <div class="field field--name-field-post-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/reseach-news" hreflang="en">Research news</a></div> </div> </span> | <span class="post-created"> 31 January 2024 </span> </div> </div> <div class="node__meta hidden"> <article typeof="schema:Person" about="/user/87" class="profile"> </article> <span> Submitted by <span rel="schema:author" class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/user/87" typeof="schema:Person" property="schema:name" datatype="">scriweb</span></span> on 31 January 2024 </span> <span property="schema:dateCreated" content="2024-01-31T20:10:40+00:00" class="rdf-meta hidden"></span> </div> <div class="node__content clearfix"> <div property="schema:text" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Kathleen Watt, PhD<br><br> Postdoctoral Fellow<br><br> Karolinska Institutet, Stockholm, Sweden<br><br> <br><br> <strong>For Zoom details, please email <a href="mailto:qcri@queensu.ca">qcri@queensu.ca</a></strong><br><br> <br><br> <span><span><strong><span lang="EN-CA"><span>“</span></span></strong><strong><span><span><span>Epigenetic coordination of transcriptional and translational </span></span></span></strong></span></span><span><span><strong><span><span><span>programs in hypoxia</span></span></span></strong><strong><span lang="EN-CA"><span>”</span></span></strong></span></span></p> <p><span><span><span><span><span><span>Brief Abstract and Bio:</span></span></span> </span></span></span></p> <p><span><span><span><span><span>I completed my PhD studies at Queen's University under the supervision of Dr. Andrew Craig, investigating the role of microRNAs in metastatic cancers. I am currently a Postdoctoral Researcher in the group of Dr. Ola Larsson at Karolinska Institutet in Stockholm. My lastest work investigates mechanisms coordinating adaptive gene expression programs in cancer. I use various wet-lab techniques and bioinformatic approaches to understand the interplay between epigenetic, transcriptional, and translational programs in hypoxia, and how the coordination of these processes contributes to cancer cell plasticity. In this talk, I will outline our recent work where we have revealed that hypoxia-induced alterations in H3K4me3 are associated with pervasive changes in transcription start site selection, leading to remodeling of 5'UTRs that act as critical hubs regulating translation. These epigenetically driven changes in mRNA isoform selection are coordinated with the stress-induced reprogramming of the translational machinery to drive adaptive gene expression programs under hypoxia.</span></span></span></span></span></p> <p><span><span><strong><span><span>Host</span></span></strong><span><span>: Lynne-Marie Postovit, PhD</span></span></span></span></p> <p> </p> </div> </div> <div id="node-single-comment"> </div> </div> </article> <!-- End Display article for detail page --> </div> </div> </div> </div> </div> </div> <!-- Sidebar Left --> <!-- End Sidebar Left --> <!-- Sidebar Right --> <div class="col-lg-4 col-md-4 col-sm-12 col-xs-12 sidebar sidebar-right theiaStickySidebar"> <div class="sidebar-inner"> <div class="region region-sidebar-right"> <div id="block-gavias-financial-subscribeandtostayinformedaboutcancerresearch" class="block block-block-content block-block-content3a677b87-9495-4373-9021-c3f9d837e48d no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><div id="mc_embed_shell"> <link href="//cdn-images.mailchimp.com/embedcode/classic-061523.css" rel="stylesheet" type="text/css"> <style type="text/css"> #mc_embed_signup{background:#fff; false;clear:left; font:14px Helvetica,Arial,sans-serif; width: 100%;font-family: "Open Sans" !important; background-color: #f6f6f6 !important; padding: 1px 0; } #mc_embed_signup h2{font-weight: 400;} #mc_embed_signup .button{background-color:#002452;} /* Add your own Mailchimp form style overrides in your site stylesheet or in this style block. We recommend moving this block and the preceding CSS link to the HEAD of your HTML file. */ </style> <div id="mc_embed_signup"> <form action="https://queensu.us18.list-manage.com/subscribe/post?u=2215ebc9866a67ad7205c37f1&id=3bf65462e0&f_id=008e2ae1f0" method="post" id="mc-embedded-subscribe-form" name="mc-embedded-subscribe-form" class="validate" target="_blank"> <div id="mc_embed_signup_scroll"><h2>Subscribe to stay informed about groundbreaking cancer research</h2> <div class="indicates-required"><span class="asterisk">*</span> indicates required</div> <div class="mc-field-group"><label for="mce-EMAIL">Email Address <span class="asterisk">*</span></label><input type="email" name="EMAIL" class="required email" id="mce-EMAIL" required="" value=""></div><div class="mc-field-group"><label for="mce-FNAME">First Name </label><input type="text" name="FNAME" class=" text" id="mce-FNAME" value=""></div><div class="mc-field-group"><label for="mce-LNAME">Last Name </label><input type="text" name="LNAME" class=" text" id="mce-LNAME" value=""></div> <div id="mce-responses" class="clear"> <div class="response" id="mce-error-response" style="display: none;"></div> <div class="response" id="mce-success-response" style="display: none;"></div> </div><div style="position: absolute; left: -5000px;" aria-hidden="true"><input type="text" name="b_2215ebc9866a67ad7205c37f1_3bf65462e0" tabindex="-1" value=""></div><div class="clear"><input type="submit" name="subscribe" id="mc-embedded-subscribe" class="button" value="Subscribe"></div> </div> </form> </div> <script type="text/javascript" src="//s3.amazonaws.com/downloads.mailchimp.com/js/mc-validate.js"></script><script type="text/javascript">(function($) {window.fnames = new Array(); window.ftypes = new Array();fnames[0]='EMAIL';ftypes[0]='email';fnames[1]='FNAME';ftypes[1]='text';fnames[2]='LNAME';ftypes[2]='text';fnames[3]='ADDRESS';ftypes[3]='address';fnames[4]='PHONE';ftypes[4]='phone';fnames[5]='MMERGE5';ftypes[5]='text';fnames[6]='MMERGE6';ftypes[6]='text';}(jQuery));var $mcj = jQuery.noConflict(true);</script></div></div> </div> </div> <div class="views-element-container block block-views block-views-blockpost-other-block-1" id="block-gavias-financial-views-block-post-other-block-1"> <h2 class="block-title" ><span>Recent Posts</span></h2> <div class="content block-content"> <div><div class="post-style-list small gva-view view view-post-other view-id-post_other view-display-id-block_1 js-view-dom-id-d7921575d4d4c9e7b6a4f07e2219786263849677fa0c18f2af51663bbba42194"> <div class="view-content"> <div class="item-list"> <ul> <li class="view-list-item" ><div class="views-field views-field-nothing"><div class="field-content"><div class="post-block"> <div class="post-title"> <a href="/news/research-news/queens-relay-life-2024-2025" hreflang="en">Queen's Relay for Life 2024-2025</a> </div> <div class="post-meta"> <span class="post-created"><time datetime="2024-10-29T08:33:49-04:00" class="datetime">29 Oct 24</time> </span> </div> </div></div></div></li> <li class="view-list-item" ><div class="views-field views-field-nothing"><div class="field-content"><div class="post-block"> <div class="post-title"> <a href="/news/research-news/canadian-cancer-society-cibc-run-cure" hreflang="en">Canadian Cancer Society CIBC Run for the Cure</a> </div> <div class="post-meta"> <span class="post-created"><time datetime="2024-10-11T11:00:06-04:00" class="datetime">11 Oct 24</time> </span> </div> </div></div></div></li> <li class="view-list-item" ><div class="views-field views-field-nothing"><div class="field-content"><div class="post-block"> <div class="post-title"> <a href="/news/research-news/advancing-cancer-treatment-together-healthier-future" hreflang="en">Advancing Cancer Treatment, Together for a Healthier Future</a> </div> <div class="post-meta"> <span class="post-created"><time datetime="2024-07-09T09:12:42-04:00" class="datetime">09 Jul 24</time> </span> </div> </div></div></div></li> <li class="view-list-item" ><div class="views-field views-field-nothing"><div class="field-content"><div class="post-block"> <div class="post-title"> <a href="/news/research-news/more-summer-students-qcri-2024" hreflang="en">More Summer Students of QCRI 2024!</a> </div> <div class="post-meta"> <span class="post-created"><time datetime="2024-04-16T11:50:37-04:00" class="datetime">16 Apr 24</time> </span> </div> </div></div></div></li> <li class="view-list-item" ><div class="views-field views-field-nothing"><div class="field-content"><div class="post-block"> <div class="post-title"> <a href="/news/research-news/summer-students-qcri-2024" hreflang="en">Summer Students of QCRI 2024!</a> </div> <div class="post-meta"> <span class="post-created"><time datetime="2024-04-16T11:46:22-04:00" class="datetime">16 Apr 24</time> </span> </div> </div></div></div></li> </ul> </div> </div> <div class="view-footer"> <a href="/news"><h4>View All <i class="fa fa-arrow-circle-right" aria-hidden="true"></i></h4></a> </div> </div> </div> </div> </div> </div> </div> </div> <!-- End Sidebar Right --> </div> </div> </div> </div> </div> </div> <footer id="footer" class="footer"> <div class="footer-inner"> <div class="footer-center"> <div class="container"> <div class="row"> <div class="footer-first col-lg-3 col-md-3 col-sm-12 col-xs-12 column"> <div class="region region-footer-first"> <div id="block-queensfooterlogo-2" class="block block-block-content block-block-contentf665d6b6-d3bf-4022-bc0c-d81efa4c3c55 no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qu_footer_branding"></section></div> </div> </div> </div> </div> <div class="footer-second col-lg-9 col-md-9 col-sm-12 col-xs-12 column"> <div class="region region-footer-second"> <div id="block-linkfooter" class="hidden-xs hidden-sm block block-block-content block-block-contente03afdfc-b255-481b-9605-5a0e153ccacf no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qhs_schools"></section></div> </div> </div> </div> </div> <div class="footer-third col-lg-12 col-md-12 col-sm-12 col-xs-12 column"> <div class="region region-footer-third"> <div id="block-contactinfomschq" class="block block-block-content block-block-contentfc5b443f-0626-414c-bca6-320b99b79ec2 no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="site_contact_social"> <section> <p class="title">Contact Us</p> <ul class="contact"> <li> <a href="/contact-us"><i class="fas fa-home"></i>Sinclair Cancer Research Institute</a> </li> <li><i class="fas fa-phone"></i> (613) 533-6507</li> <li> <a href="mailto:scri@queensu.ca"><i class="fas fa-envelope"></i>scri@queensu.ca</a> </li> </ul> </section> <section> <p class="title">Follow Us</p> <ul class="social"> <li> <a href="https://www.facebook.com/qcri.queensu.ca" target="_blank"><i class="fa fa-facebook-square"></i></a> </li> <li> <a href="https://x.com/QueensuSCRI"><i class="fa fa-twitter"></i></a> </li> </ul> </section> </section></div> </div> </div> </div> </div> <div class="footer-four col-lg-12 col-md-12 col-sm-12 col-xs-12 column"> <div class="region region-footer-four"> <div id="block-partnerhospitals" class="block block-block-content block-block-content8ab147ed-cc29-4ef9-bc72-c820a7b48480 no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qhs_hospitals"></section></div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="copyright"> <div class="container"> <div class="copyright-inner"> <div class="region region-copyright"> <div id="block-gavias-financial-copyright" class="block block-block-content block-block-content6a74724d-d485-4216-a560-962e52758fde no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qhs_copyright"></section></div> </div> </div> </div> </div> </div> </div> </footer> </div> <script src="/sites/scri/files/js/js_XYCYgMo7sNxRjcd1wJJu_CthRlXRV3GfXV5rKz3J60c.js?scope=footer&delta=0&language=en&theme=gavias_financial&include=eJx1kFFygzAMRC_k2EdihBFEQbYykqChp6-nDSUp0x-P9aRdy2sImq8dLC5Zyp3RMfkVC8ZClQpwzGYhi2IadLm3-nU02GaOJfVgGDKD2fZ2L2gGEz4NqmgzpE8ME6wE1o1UoWYCThNLD3wx35jqdO7f7DKKOOq5JSuq0tAeObv-gGMCH9785_0rzzKshB-Wvs9YZFgY3xDc4BHMwcmcsu3qg4SWl05Y89YBo7qlv2DfzbjtoQwbajqj2EJDtziqVMc67KqeJc_9Qjwcslf2n-6UxC-INlONPS_4BVM_yis"></script> <script src="https://www.queensu.ca/resources/emergencyalerts/js/axios.min.js" defer=""></script> <script src="https://www.queensu.ca/resources/emergencyalerts/js/react.production.min.js" defer=""></script> <script src="https://www.queensu.ca/resources/emergencyalerts/js/react-dom.production.min.js" defer=""></script> <script src="https://www.queensu.ca/resources/emergencyalerts/js/emergencyalerts.js" defer=""></script> <script src="/sites/scri/files/js/js__8tf_wZZ5XqmwyotJYf4vEzXeSzET1RvqFryEu38vR8.js?scope=footer&delta=5&language=en&theme=gavias_financial&include=eJx1kFFygzAMRC_k2EdihBFEQbYykqChp6-nDSUp0x-P9aRdy2sImq8dLC5Zyp3RMfkVC8ZClQpwzGYhi2IadLm3-nU02GaOJfVgGDKD2fZ2L2gGEz4NqmgzpE8ME6wE1o1UoWYCThNLD3wx35jqdO7f7DKKOOq5JSuq0tAeObv-gGMCH9785_0rzzKshB-Wvs9YZFgY3xDc4BHMwcmcsu3qg4SWl05Y89YBo7qlv2DfzbjtoQwbajqj2EJDtziqVMc67KqeJc_9Qjwcslf2n-6UxC-INlONPS_4BVM_yis"></script> </body> </html>